C-Reactive Protein in Cardiovascular Disease
نویسندگان
چکیده
منابع مشابه
C-reactive protein and cardiovascular disease.
Paul M Ridker, MD, MPH, and Nader Rifai, PhD, eds 393 pages. St-Laurent, Canada: MediEdition Inc; 2006. $68.99. ISBN 0-9780090-0-2. Few biomarkers of disease have generated as much interest, promise, and debate as C-reactive protein (CRP). CRP, a hepatically derived pentraxin, was discovered in 1930 by Rockefeller University investigators William Tillett and Thomas Francis in patients with pneu...
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C-reactive protein (CRP), a blood marker of inflammation and a hallmark of the acute-phase response, has been shown to be a powerful and specific predictor of cardiovascular event risk in populations of otherwise healthy persons. Here we review what is known about CRP gene polymorphisms, discuss how these might affect the epidemiology of CRP and our understanding of CRP's contribution to cardio...
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C-reactive protein (CRP) performs two recognition functions that are relevant to cardiovascular disease. First, in its native pentameric conformation, CRP recognizes molecules and cells with exposed phosphocholine (PCh) groups, such as microbial pathogens and damaged cells. PCh-containing ligand-bound CRP activates the complement system to destroy the ligand. Thus, the PCh-binding function of C...
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Recent pre-clinical and clinical studies have revealed the C-reactive protein gene (CRP) is related to the degree of acute rise in plasma C-reactive protein (CRP) levels. Moreover, single nucleotide polymorphisms (SNPs) in the CRP gene could associate with increased risk of cancer, atherosclerosis, diabetes mellitus, bowel disease, rheumatoid arthritis, psoriasis, obstructive pulmonary disease,...
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C-reactive protein (CRP), a marker of inflammation, is directly involved in atherogenesis, and elevated CRP levels (as measured by highly sensitive assays) are associated with increased cardiovascular risk. We welcome the recent joint guidelines on CRP testing from the Centers for Disease Control and Prevention and the American Heart Association; however, whereas the guidelines suggest measurin...
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ژورنال
عنوان ژورنال: EAS Journal of Medicine and Surgery
سال: 2020
ISSN: 2663-1857,2663-7332
DOI: 10.36349/easjms.2020.v02i11.001